Concepedia

PPARG2 Pro12Ala and ADAMTS9 rs4607103 as “insulin resistance loci” and “insulin secretion loci” in Italian individuals. The GENFIEV study and the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 4

Maddalena Trombetta, Simone Bonetti, Maria Linda Boselli, Roberto Miccoli, Giovanni Malerba, Enzo Bonora, Stefano Del Prato, Riccardo C. Bonadonna

Acta Diabetologica · 2012 · 37 citations · 20 references

DOI

Concepts

References

20

The Metabolic Syndrome is an independent predictor of cardiovascular disease in Type 2 diabetic subjects. Prospective data from the Verona Diabetes Complications Study

Enzo Bonora, Giovanni Targher, G. Formentini et al. · Diabetic Medicine · 2003 · 292 citations

, , +17

Brain PPAR-γ promotes obesity and is required for the insulin–sensitizing effect of thiazolidinediones

Min Lü, David A. Sarruf, Saswata Talukdar et al. · Nature Medicine · 2011 · 228 citations

, , +14

Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes.

Francesco Paolo Mancini, Olga Vaccaro, Lina Sabatino et al. · Diabetes · 1999 · 165 citations

, , +13

Association Testing of Novel Type 2 Diabetes Risk Alleles in the <i>JAZF1</i>, <i>CDC123</i>/<i>CAMK1D</i>, <i>TSPAN8</i>, <i>THADA</i>, <i>ADAMTS9</i>, and <i>NOTCH2</i> Loci With Insulin Release, Insulin Sensitivity, and Obesity in a Population-Based Sample of 4,516 Glucose-Tolerant Middle-Aged Danes

Niels Grarup, Nikolaj T. Krarup, Anders Albrechtsen et al. · Diabetes · 2008 · 162 citations · Full text

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Piragliatin (RO4389620), a Novel Glucokinase Activator, Lowers Plasma Glucose Both in the Postabsorptive State and after a Glucose Challenge in Patients with Type 2 Diabetes Mellitus: A Mechanistic Study

Riccardo C. Bonadonna, Tim Heise, Christophe Arbet‐Engels et al. · The Journal of Clinical Endocrinology & Metabolism · 2010 · 143 citations · Full text

, , +14