David A. Sarruf

Obesity is associated with hypothalamic injury in rodents and humans

Joshua P. Thaler, Chun‐Xia Yi, Ellen A. Schur et al. · Journal of Clinical Investigation · 2011 · 1.8K citations

Hypothalamic Injury, Reactive Gliosis, High-fat Diet +19

Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats

David A. Sarruf, Joshua P. Thaler, Gregory J. Morton et al. · Diabetes · 2010 · 281 citations · Full text

Peroxisome proliferation–associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity

Sabrina Diano, Jin Kwon Jeong, Marcelo O. Dietrich et al. · Nature Medicine · 2011 · 266 citations

Obesity, Nutrition, Metabolic Syndrome +13

Brain PPAR-γ promotes obesity and is required for the insulin–sensitizing effect of thiazolidinediones

Min Lü, David A. Sarruf, Saswata Talukdar et al. · Nature Medicine · 2011 · 228 citations

Obesity, Metabolic Syndrome, Energy Homeostasis +13

Leptin Activates a Novel CNS Mechanism for Insulin-Independent Normalization of Severe Diabetic Hyperglycemia

Jonathan P. German, Joshua P. Thaler, Brent E. Wisse et al. · Endocrinology · 2010 · 169 citations · Full text