Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology · 2007 · 12.6K citations

Novel Mechanism, Systems Biology, Natural Sciences +10

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Johan Skog, Tom Würdinger, Sjoerd van Rijn et al. · Nature Cell Biology · 2008 · 4.9K citations

Neuro-oncology, Glioma, Tumour Growth +10

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Héctor Peinado, Maša Alečković, Simon Lavotshkin et al. · Nature Medicine · 2012 · 3.6K citations · Full text

Exosomes, Medicine, Melanoma +12

Circulating mutant DNA to assess tumor dynamics

Frank Diehl, Kerstin Schmidt, Michael A. Choti et al. · Nature Medicine · 2008 · 2.7K citations · Full text

Tumor Biology, Nucleic Acid Biomarkers, Tumor Heterogeneity +8

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

Khalid Al‐Nedawi, Brian Meehan, Johann Micallef et al. · Nature Cell Biology · 2008 · 2K citations

Intercellular Transfer, Oncogenic Receptor Egfrviii, Tumour Cells +7