Concepedia

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

Angela T. Noon, Atsushi Shibata, Nicole Rief, Markus Löbrich, Grant S. Stewart, Penelope A. Jeggo, Aaron A. Goodarzi

Nature Cell Biology · 2010 · 332 citations · 36 references

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36

SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

D. Schultz, Kasirajan Ayyanathan, Dmitri Negorev et al. · Genes & Development · 2002 · 1.3K citations · Full text

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RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins

Niels Mailand, Simon Bekker‐Jensen, Helene Faustrup et al. · Cell · 2007 · 1.1K citations · Full text

, , +15

Requirement of the MRN complex for ATM activation by DNA damage

Tamar Uziel, Yaniv Lerenthal, Lilach Moyal et al. · The EMBO Journal · 2003 · 1.1K citations · Full text

, , +14

ATM and DNA-PK Function Redundantly to Phosphorylate H2AX after Exposure to Ionizing Radiation

Tom Stiff, Mark O’Driscoll, Nicole Rief et al. · Cancer Research · 2004 · 995 citations · Full text

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RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

Carsten Doil, Niels Mailand, Simon Bekker‐Jensen et al. · Cell · 2009 · 915 citations · Full text

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