Solid phase synthesis of directly linked peptide-oligodeoxynucleotide hybrids using standard synthesis protocols

1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive

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Natural Sciences, Chemistry, Pharmacology +7

New coupling reagents in peptide chemistry

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Natural Sciences, Biochemistry, Chemistry +8

Synthetic methods for the implementation of encoded combinatorial chemistry

John Nielsen, Sydney Brenner, Kim D. Janda · Journal of the American Chemical Society · 1993 · 253 citations

Pharmacy, Chemistry, Combinatorial Chemistry +8

The allylic protection method in solid-phase oligonucleotide synthesis. An efficient preparation of solid-anchored DNA oligomers

Yoshihiro Hayakawa, Shigeharu Wakabayashi, Hisatoyo Kato et al. · Journal of the American Chemical Society · 1990 · 181 citations

Pharmacy, Molecular Biology, Bioorthogonal Chemistry +9

Allyloxycarbonyl group: a versatile blocking group for nucleotide synthesis

Yoshihiro Hayakawa, Hisatoyo Kato, Mamoru Uchiyama et al. · The Journal of Organic Chemistry · 1986 · 125 citations

Natural Sciences, Biochemistry, Chemistry +7