Frequent occurrence of CYP2D610 duplication allele in a Japanese population

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

Christoph Sachse, Jürgen Brockmöller, Steffen Bauer et al. · PubMed · 1997 · 979 citations

Medicine, Genetics, Pharmacology +17

Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine.

Ida Johansson, E Lundqvist, Leif Bertilsson et al. · Proceedings of the National Academy of Sciences · 1993 · 647 citations

Medicine, Genetics, Molecular Genetics +17

Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.

Inger Johansson, Mikael Oscarson, Qun‐Ying Yue et al. · Molecular Pharmacology · 1994 · 430 citations

Medicine, Genetics, Molecular Genetics +16

Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles.

Eleni Aklillu, Irene Persson, Leif Bertilsson et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 396 citations

Life Sciences, Genetics, Pharmacology +17

Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis.

Marja­‐Liisa Dahl, Inger Johansson, Leif Bertilsson et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 314 citations

Medicine, Genetics, Molecular Genetics +17