Kan Chiba

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

Kan Chiba, Anthony J. Trevor, Neal Castagnoli · Biochemical and Biophysical Research Communications · 1984 · 1.1K citations

Life Sciences, Neuroscience, Pharmacology +14

Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells

Yoshio Kameyama, Keiko Yamashita, Kaoru Kobayashi et al. · Pharmacogenetics and Genomics · 2005 · 378 citations

Life Sciences, Biochemistry, Molecular Biology +9

Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations

Joyce A. Goldstein, Takashi Ishizaki, Kan Chiba et al. · Pharmacogenetics · 1997 · 353 citations

Life Sciences, Genetics, Pharmacology +17

Genotyping of S-mephenytoin 4′-hydroxylation in an extended Japanese population*

Takahiro Kubota, Kan Chiba, Takashi Ishizaki · Clinical Pharmacology & Therapeutics · 1996 · 288 citations

Medicine, Genetics, Pharmacology +17

Substrate Specificity of Carboxylesterase Isozymes and Their Contribution to Hydrolase Activity in Human Liver and Small Intestine

Teruko Imai, Megumi Taketani, Mayumi Shii et al. · Drug Metabolism and Disposition · 2006 · 279 citations

Life Sciences, Biochemistry, Molecular Biology +15