Assay and Disposition of Carvedilol Enantiomers in Humans and Monkeys: Evidence of Stereoselective Presystemic Metabolism

A pharmacokinetic analysis program (multi) for microcomputer.

Kiyoshi Yamaoka, Yusuke Tanigawara, Terumichi Nakagawa et al. · Journal of Pharmacobio-Dynamics · 1981 · 2.5K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12

Influence of First-Pass Effect on Availability of Drugs on Oral Administration

M. Gibaldi, R N Boyes, Stuart Feldman · Journal of Pharmaceutical Sciences · 1971 · 272 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Differential stereoselective metabolism of metoprolol in extensive and poor debrisoquin metabolizers

M. S. Lennard, Geoffrey T. Tucker, J H Silas et al. · Clinical Pharmacology & Therapeutics · 1983 · 211 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Pharmacokinetics and disposition of carvedilol in humans.

G. Neugebauer, W. Akpan, E von Möllendorff et al. · PubMed · 1987 · 124 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

Pharmacological Profile of Carvedilol as a β-Blocking Agent with Vasodilating and Hypotensive Properties

G. Sponer, W. Bartsch, K. Strein et al. · Journal of Cardiovascular Pharmacology · 1987 · 105 citations

Medicine, Cardiology, Pharmacology +17