Histone H2AX phosphorylation as a molecular pharmacological marker for DNA interstrand crosslink cancer chemotherapy

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.7K citations

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

Tanya T. Paull, Emmy P. Rogakou, Vikky Yamazaki et al. · Current Biology · 2000 · 2.1K citations · Full text

Histone Modifications, Dna Damage, Epigenetic Change +16

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

Kai Rothkamm, Markus Löbrich · Proceedings of the National Academy of Sciences · 2003 · 1.6K citations · Full text

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

Arkady Celeste, Óscar Fernández-Capetillo, Michael J. Kruhlak et al. · Nature Cell Biology · 2003 · 983 citations

Histone Modifications, Chromatin, Genome Instability +15

Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues.

Brent C. Behrens, Thomas C. Hamilton, Hidetaka Masuda et al. · PubMed · 1987 · 500 citations

Chemoprevention Strategy, Oncogenic Agent, Medicine +12