Concepedia

Histone-dna Interactions

Histone-DNA Interactions is a biophysical mechanism that mediates the sequence-specific and non-covalent association between histone proteins and DNA, governing nucleosome stability, positioning, and higher-order chromatin structure through electrostatic, hydrogen bonding, and hydrophobic forces.

1.8K

Publications

130.1K

Citations

5.4K

Authors

1.2K

Institutions

Publications per year

2017–2026

209

Parents

Publications

1.8K

New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning

Peggy T. Lowary, Jonathan Widom · Journal of Molecular Biology · 1998 · 1.9K citations

, , +16

Histone H3.1 and H3.3 Complexes Mediate Nucleosome Assembly Pathways Dependent or Independent of DNA Synthesis

Hideaki Tagami, Dominique Ray-Gallet, Geneviève Almouzni et al. · Cell · 2004 · 1.3K citations · Full text

, , +12

Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

Kirk Clark, E.D. Halay, Eseng Lai et al. · Nature · 1993 · 1.3K citations

, , +14

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

Daniel Y. Lee, Jeffrey J. Hayes, Dmitry Pruss et al. · Cell · 1993 · 1.1K citations

, , +15

Regulation of HP1–chromatin binding by histone H3 methylation and phosphorylation

Wolfgang Fischle, Boo Shan Tseng, Holger L. Dormann et al. · Nature · 2005 · 987 citations

, , +13

1–5 of 1.8K

Authors

5.4K

  1. JT
    Jean Thomas

    University of Cambridge, United Kingdom

    30 publications · 3.9K citations

    26

    h-index

  2. JJ
    Jeffrey J. Hayes

    University of Rochester Medical Center, United States

    26 publications · 3.1K citations

    23

    h-index

  3. EM
    E. Morton Bradbury

    Portsmouth College, United Kingdom

    30 publications · 2.2K citations

    23

    h-index

  4. CC
    Colyn Crane‐Robinson

    Portsmouth College, United Kingdom

    20 publications · 2.1K citations

    17

    h-index

  5. AP
    Alan P. Wolffe

    National Institutes of Health, United States

    17 publications · 2.5K citations

    16

    h-index

1–5 of 5.4K

Institutions

1.2K

  1. National Institutes of Health

    Bethesda, United States

    46 h-index

    181 publications

    22.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    36 h-index

    83 publications

    15.6K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    33 h-index

    190 publications

    14.6K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    32 h-index

    130 publications

    18.7K citations

  5. National Cancer Institute

    Bethesda, United States

    25 h-index

    64 publications

    8.2K citations

  6. Rockefeller University

    New York, United States

    23 h-index

    84 publications

    25.1K citations

  7. Pennsylvania State University

    State College, United States

    23 h-index

    82 publications

    8.5K citations

  8. University of Massachusetts Chan Medical School

    Worcester, United States

    21 h-index

    85 publications

    4K citations

1–8 of 1.2K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 95 publications · 9.3K citations

    61

    h-index

  2. Journal of Biological Chemistry

    JBC · 164 publications · 11.4K citations

    60

    h-index

  3. Nucleic Acids Research

    153 publications · 9.4K citations

    55

    h-index

  4. Journal of Molecular Biology

    JMB · 77 publications · 8K citations

    44

    h-index

  5. The EMBO Journal

    43 publications · 6.1K citations

    40

    h-index

1–5