Concepedia

Alan P. Wolffe

AP

139

Publications

19.6K

Citations

71

H-Index

1983

Active since

Affiliations

National Institutes of Health(Current)

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institute of Child Health

Sangamo BioSciences (United States)

National Institute of Child Health

Alan P. Wolffe is an author at National Institutes of Health specializing in medicine, chromatin, and natural sciences.

Top concepts

MedicineChromatinNatural SciencesGeneticsEpigeneticsGene ExpressionMolecular BiologyChromatin StructureChromatin FunctionTranscriptional Regulation

Publications per year

1983–2003

139

Publications

139

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

Peter Lloyd Jones, Gert Jan C. Veenstra, Paul A. Wade et al. · Nature Genetics · 1998 · 2.7K citations

Histone Modifications, Chromatin, Transcriptional Regulation +14

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

Daniel Y. Lee, Jeffrey J. Hayes, Dmitry Pruss et al. · Cell · 1993 · 1.1K citations

Histone Modifications, Epigenetic Change, Genetics +17

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

Keith D. Robertson, Slimane Ait‐Si‐Ali, Tomoki Yokochi et al. · Nature Genetics · 2000 · 938 citations

Chromatin, Transcriptional Regulation, Medicine +11

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

Paul A. Wade, Anne Gégonne, Peter Lloyd Jones et al. · Nature Genetics · 1999 · 806 citations

Histone Modifications, Chromatin, Chromatin Structure +15

Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III

Christin Tse, Takashi Sera, Alan P. Wolffe et al. · Molecular and Cellular Biology · 1998 · 566 citations · Full text

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