High throughput UV method for the estimation of thermodynamic solubility and the determination of the solubility in biorelevant media

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Evaluation of Various Dissolution Media for Predicting In Vivo Performance of Class I and II Drugs

Eric Galia, Eleftheria Nicolaides, D. Hörter et al. · Pharmaceutical Research · 1998 · 923 citations

Pharmacy, Pharmaceutics, Pharmacology +16

A High-Throughput Screening Method for the Determination of Aqueous Drug Solubility Using Laser Nephelometry in Microtiter Plates

Christopher Bevan, Richard Lloyd · Analytical Chemistry · 2000 · 349 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +9

Estimation of the Increase in Solubility of Drugs as a Function of Bile Salt Concentration

Sabena Dawoodali Mithani, Vassiliki Bakatselou, Christopher TenHoor et al. · Pharmaceutical Research · 1996 · 300 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +11