Concepedia

Biorelevant Solubility

Biorelevant Solubility is a pharmacokinetic solubility assessment that characterizes the dissolution behavior of a drug in physiological media simulating the composition and conditions of specific gastrointestinal fluids to predict in vivo solubility and absorption.

84

Publications

4.3K

Citations

381

Authors

120

Institutions

Publications per year

2017–2026

40

Parents

Publications

84

Biorelevant Dissolution Testing to Predict the Plasma Profile of Lipophilic Drugs After Oral Administration

Eleftheria Nicolaides, Moira Symillides, Jennifer Dressman et al. · Pharmaceutical Research · 2001 · 208 citations

, , +16

Dissolution Rate and Apparent Solubility of Poorly Soluble Drugs in Biorelevant Dissolution Media

Jonas H. Fagerberg, Oksana Tsinman, Na Sun et al. · Molecular Pharmaceutics · 2010 · 184 citations

, , +17

Forecasting the Oral Absorption Behavior of Poorly Soluble Weak Bases Using Solubility and Dissolution Studies in Biorelevant Media

Edmund Kostewicz, Ulrich Brauns, Robert R. Becker et al. · Pharmaceutical Research · 2002 · 181 citations

, , +17

Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling

Yasushi Shono, Ekarat Jantratid, Niels Janssen et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2009 · 158 citations

, , +16

Achieving Antral Grinding Forces in Biorelevant In Vitro Models: Comparing the USP Dissolution Apparatus II and the Dynamic Gastric Model with Human In Vivo Data

Maria Vardakou, Annalisa Mercuri, S. A. Barker et al. · AAPS PharmSciTech · 2011 · 158 citations · Full text

, , +16

1–5 of 84

Authors

381

  1. JD
    Jennifer Dressman

    Goethe University Frankfurt, Germany

    14 publications · 1.2K citations

    13

    h-index

  2. CR
    Christos Reppas

    National and Kapodistrian University of Athens, Greece

    9 publications · 747 citations

    9

    h-index

  3. MV
    Maria Vertzoni

    National and Kapodistrian University of Athens, Greece

    8 publications · 693 citations

    8

    h-index

  4. NF
    Nikoletta Fotaki

    University of Bath, United Kingdom

    5 publications · 354 citations

    5

    h-index

  5. AM
    Anette Müllertz

    University of Copenhagen, Denmark

    5 publications · 232 citations

    5

    h-index

1–5 of 381

Institutions

120

  1. Goethe University Frankfurt

    Frankfurt am Main, Germany

    14 h-index

    36 publications

    2.9K citations

  2. National and Kapodistrian University of Athens

    Athens, Greece

    8 h-index

    26 publications

    2K citations

  3. FHNW University of Applied Sciences and Arts Northwestern Switzerland

    Windisch, Switzerland

    5 h-index

    10 publications

    255 citations

  4. University of Copenhagen

    Copenhagen, Denmark

    4 h-index

    15 publications

    639 citations

  5. Fraunhofer Institute for Translational Medicine and Pharmacology

    Frankfurt am Main, Germany

    4 h-index

    5 publications

    152 citations

  6. Simcyp (United Kingdom)

    Sheffield, United Kingdom

    4 h-index

    8 publications

    503 citations

  7. Ben-Gurion University of the Negev

    Beersheba, Israel

    3 h-index

    9 publications

    335 citations

  8. Roche (Switzerland)

    Basel, Switzerland

    3 h-index

    10 publications

    694 citations

1–8 of 120

Venues

  1. Molecular Pharmaceutics

    11 publications · 634 citations

    11

    h-index

  2. European Journal of Pharmaceutical Sciences

    10 publications · 505 citations

    10

    h-index

  3. European Journal of Pharmaceutics and Biopharmaceutics

    EJPB · 8 publications · 528 citations

    8

    h-index

  4. Dissolution Technologies

    6 publications · 337 citations

    6

    h-index

  5. Journal of Pharmaceutical Sciences

    6 publications · 219 citations

    6

    h-index

1–5