Concepedia

Phase I and pharmacologic study of irinotecan in combination with cisplatin for advanced lung cancer

N Masuda, M. Fukuoka, S. Kudoh, Y Kusunoki, Kunihiko Matsui, Nobuhide Takifuji, Kazuhiko Nakagawa, M Tamanoi, Takashi Nitta, T. Hirashima,

British Journal of Cancer · 1993 · 94 citations · 15 references

DOIFull text

Open access

Concepts

References

15

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

, , +15

WHO handbook for reporting results of cancer treatment

Richard Sylvester · Controlled Clinical Trials · 1980 · 1.1K citations

, , +11

Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin.

Yaw Huei Hsiang, Leroy F. Liu · PubMed · 1988 · 844 citations

, , +12

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

Robert Hertzberg, Mary Jo Caranfa, Sidney M. Hecht · Biochemistry · 1989 · 552 citations

, , +10

CPT-11: a new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer.

N Masuda, M. Fukuoka, Y Kusunoki et al. · Journal of Clinical Oncology · 1992 · 452 citations

, , +8