Effect of Stemona curtisii root extract on P-glycoprotein and MRP-1 function in multidrug-resistant cancer cells

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3.1K citations

Medicine, Molecular Biology, Oncology +16

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

Kevin E. Noonan, Christian Beck, Tatyana A. Holzmayer et al. · Proceedings of the National Academy of Sciences · 1990 · 729 citations · Full text

Medicine, Oncology, Pharmacology +14

Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins.

Donglai Shen, Carol Cardarelli, Jinyoung Hwang et al. · Journal of Biological Chemistry · 1986 · 467 citations · Full text

Medicine, Molecular Biology, Oncology +15

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood.

Helen S. L. Chan, Paul S. Thorner, George Haddad et al. · Journal of Clinical Oncology · 1990 · 454 citations

Medicine, Oncology, Pharmacology +17

Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis.

Suresh V. Ambudkar, Isabelle H. Lelong, J Zhang et al. · Proceedings of the National Academy of Sciences · 1992 · 397 citations

Life Sciences, Biochemistry, Pharmacology +17