Studies on protective effects of human paraoxonases 1 and 3 on atherosclerosis in apolipoprotein E knockout mice

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

Mira Rosenblat, C L Bisgaier, Roger S. Newton et al. · Journal of Clinical Investigation · 1998 · 1.2K citations · Full text

Life Sciences, Biochemistry, Lipid Biochemistry +16

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

Diana M. Shih, Lingjie Gu, Yu-Rong Xia et al. · Nature · 1998 · 1.1K citations

Pharmacy, Biochemistry, Toxicology +9

ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation

Matthew A. Kennedy, Gabriel Barrera, Kotoka Nakamura et al. · Cell Metabolism · 2005 · 874 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice

Hirokazu Kirii, Tamikazu Niwa, Yasuhiro Yamada et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2003 · 739 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities

Dragomir Draganov, John F. Teiber, Audrey Speelman et al. · Journal of Lipid Research · 2005 · 707 citations · Full text

Life Sciences, Biochemistry, Biotechnology +9