Attempts to introduce chemotherapeutic nucleotides into cells: studies on the anti-HIV agent FDT

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

Hiroaki Mitsuya, Kent J. Weinhold, P A Furman et al. · Proceedings of the National Academy of Sciences · 1985 · 1.9K citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

Hiroaki Mitsuya, S Broder · Proceedings of the National Academy of Sciences · 1986 · 1K citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

A novel method for phosphorylation of nucleosides to 5′-nucleotides

Masaharu Yoshikawa, Tetsuya Kato, Tadao Takenishi · Tetrahedron Letters · 1967 · 489 citations

Pharmacy, Biochemistry, Molecular Biology +9

Some studies of the active intermediates formed in the microsomal metabolism of cyclophosphamide and isophosphamide

T.A. Connors, Peter J. Cox, Peter B. Farmer et al. · Biochemical Pharmacology · 1974 · 344 citations

Medicine, Biochemistry, Pharmacology +12

Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate

P A Furman, M H St Clair, James A. Fyfe et al. · Journal of Virology · 1979 · 328 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14