Simultaneous pharmacokinetic and pharmacodynamic modeling

Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to <i>d</i>‐tubocurarine

Lewis B. Sheiner, Donald R. Stanski, Samuel Vožeh et al. · Clinical Pharmacology & Therapeutics · 1979 · 1.1K citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Bioavailability -- A Problem in Equivalence

Carl M. Metzler · Biometrics · 1974 · 638 citations

Pharmacy, Biostatistics, Pharmacology +10

Kinetics of pharmacologic response I. Proposed relationships between response and drug concentration in the intact animal and man

John G. Wagner · Journal of Theoretical Biology · 1968 · 305 citations

Medicine, Pharmacokinetics, Pharmacology +13

Pharmacokinetic and pharmacodynamic tolerance of a new anticonvulsant agent (3-sulfamoylmethyl-1,2-benzisoxazole) compared to phenobarbital, diphenylhydantoin and carbamazepine in rats.

Yuichi Masuda, Yuzo Utsui, Yuko Shiraishi et al. · PubMed · 1979 · 17 citations

Medicine, Pharmacokinetics, Pharmacology +9