Concepedia
European Journal of Medicinal Chemistry · 2012 · 10 citations · 55 references
Open access
Life SciencesMedicinal ChemistryPharmacologyDrug DesignDrug DiscoveryComplement RegulationComplement SystemEnzyme InhibitionComplement Activation PathwaysComplex Molecule FunctionalizationSmall-molecule Complement Inhibitors
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Soluble Human Complement Receptor Type 1: In Vivo Inhibitor of Complement Suppressing Post-Ischemic Myocardial Inflammation and Necrosis
Harlan F. Weisman, Michelle K. Leppo, Henry C. Marsh et al. · Science · 1990 · 979 citations
Life Sciences, Immunology, Pharmacology +17
Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria
Russell P. Rother, Scott A. Rollins, Christopher F. Mojcik et al. · Nature Biotechnology · 2007 · 764 citations
Life Sciences, Immunology, Pharmacology +13
Palladium-catalyzed carboalkoxylation of aryl, benzyl, and vinylic halides
A. SCHOENBERG, I. Bartoletti, Richard F. Heck · The Journal of Organic Chemistry · 1974 · 735 citations
Natural Sciences, Chemistry, Catalysis +10
Strategies for nucleophilic, electrophilic, and radical trifluoromethylations
Jun‐An Ma, Dominique Cahard · Journal of Fluorine Chemistry · 2007 · 560 citations
Natural Sciences, Chemistry, Medicinal Chemistry +10
Pexelizumab for Acute ST-Elevation Myocardial Infarction in Patients Undergoing Primary Percutaneous Coronary Intervention
JAMA · 2007 · 440 citations · Full text
Medicine, Cardiology, Pharmacology +17