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Pneumococcal Bacteremia with Especial Reference to Bacteremic Pneumococcal Pneumonia

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Article1 May 1964Pneumococcal Bacteremia with Especial Reference to Bacteremic Pneumococcal PneumoniaROBERT AUSTRIAN, M.D., JEROME GOLD, M.D.ROBERT AUSTRIAN, M.D., JEROME GOLD, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-5-759 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTwenty-five years have elapsed since the subject of pneumococcal bacteremia has been reviewed (1, 2). In that period many changes have taken place both in the treatment of this disorder and in the attitude of the medical profession toward it. The introduction of a series of antimicrobial drugs effective against all capsular types of pneumococcus has led to widespread abandonment of the more precise bacteriologic techniques designed for the recognition of this organism and secondarily to the impression that pneumococcal disease no longer constitutes a serious medical problem. To determine the validity of these practices and attitudes, established techniques for...References1. TILGHMANFINLAND RCM: Clinical significance of bacteremia in pneumococcal pneumonia. Arch. Intern. Med. (Chicago) 59: 602, 1937. CrossrefGoogle Scholar2. BULLOWA JG: The Management of the Pneumonias, Oxford University Press, New York, 1937. Google Scholar3. MACLEODAUSTRIANFINLAND CMRM: Pneumococcus, in Diagnostic Procedures and Reagents, American Public Health Association, New York, 1963, pp. 222-30. Google Scholar4. Statistical Abstract of the United States, 1958, 79th Annual Edition: U. S. Department of Commerce, Bureau of the Census, U. S. Government Printing Office, Washington, D. C., 1958, p. 6. Google Scholar5. DINGLEBADGERFELLERHODGESJORDANRAMMELKAMP JHGFAERGWSCH: A study of illness in a group of Cleveland families. I. Plan of study and certain general observations. Amer. J. Hyg. 58: 16, 1953. MedlineGoogle Scholar6. REIMANN HA: Current problems of the pneumonias. Ann. Intern. 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JETERMCKEEMASON WSAPRJ: Inhibition of immune phagocytosis of Diplococcus pneumoniae by human neutrophiles with antibody against complement. J. Immun. 86: 386, 1961. MedlineGoogle Scholar13. DOWLINGLEPPER HFMH: The effect of antibiotics (Penicillin, Aureomycin, and Terramycin) on the fatality rate and incidence of complications in pneumococcic pneumonia. Amer. J. Med. Sci. 222: 396, 1951. CrossrefMedlineGoogle Scholar14. MACLEODHODGESHEIDELBERGERBERNHARD CMRGMWG: Prevention of pneumococcal pneumonia by immunization with specific capsular polysaccharides. J. Exp. Med. 82: 445, 1945. CrossrefGoogle Scholar15. KAUFMAN P: Pneumonia in old age. Arch. Intern. Med. (Chicago) 79: 518, 1947. CrossrefGoogle Scholar16. HEIDELBERGER M: Persistence of antibodies in man after immunization, in The Nature and Significance of the Antibody Response, edited by PAPPENHEIMER, A. M., JR., Columbia University Press, New York, 1953, pp. 90-101. Google Scholar17. HEIDELBERGERMACLEODDI LAPI MCMM: The human antibody response to simultaneous injection of six specific polysaccharides of pneumococcus. J. Exp. Med. 88: 369, 1948. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, PennsylvaniaFrom the Department of Medicine, State University of New York Downstate Medical Center, the Medical Service of Kings County Hospital, Brooklyn, New York, and the Department of Research Medicine, the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.These data were presented in part at the 76th Session of the Association of American Physicians, April 30, 1963.Requests for reprints should be addressed to Robert Austrian, M.D., Hospital of the University of Pennsylvania, Philadelphia 4, Pennsylvania. 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clinical with Streptococcus pneumoniaeInvasive Pneumococcal Infections Hospitalized Children in an on current Challenge of Lower Respiratory Tract and Macrolide Resistance in Pneumococcal Pneumonia: Does In Resistance Clinical of antimicrobial resistance in the management of pneumococcal community-acquired Bacteremia: to in the Epidemiology of Pneumococcal Bacteremia in a University Hospital During a Carriage of Streptococcus pneumoniae by Adults and Children in Community and Clinical Trial with for Patients with Community-Acquired Pneumococcal of Community-Acquired Pneumonia Caused by Streptococcus Respiratory InfectionsThe Clinical Significance of Streptococcus pneumoniae: of Mice with against Streptococcus pneumoniae in community-acquired pneumoniaA to Macrolide pneumococcal infections in patients without the impact of resistance on Commentary: is Antimicrobial Therapy for Bacteremic Pneumococcal of Pneumococcal Polysaccharide Review of in the Management of Patients with Community-Acquired and J. Pneumococcal Endocarditis and that and Resistance to en la for the Treatment of Community-Acquired Pneumonia in vaccination en chez future the development of new antimicrobial infections: of the School of Disease on 3 in Pneumococcal Implications for the of Pneumococcal Conjugate of Macrolide Antibiotic Treatment in Patients with Bacteremia to Streptococcus of Pneumococcal Pneumonia in in of pneumococcal disease in HIV-infected mortality and with Pneumococcal Conjugate Vaccines with a of as against Pneumococcal Infections in and pneumococcal pneumonia: treatment with and les pneumonies communautaires à pneumocoque chez des in lower respiratory tract infections and the impact of antimicrobial the of to Streptococcus Infection due to Streptococcus of appropriate antibiotic use for treatment of respiratory tract infections in specific and of Antibiotic Use for Treatment of Respiratory Tract Infections in Adults: and J. and A. and COPD in Severe Community-Acquired anti-pneumococcique : place et dans la des infections communautaires des respiratoires of and specific antibody on bacterial and in experimental pneumococcal pneumoniaThe of the severity of community-acquired pneumonia on the of blood Urinary Antigen for the of Pneumococcal of Streptococcus pneumoniae in the United Antibiotic and pneumococcal a factors for community-acquired pneumonia pneumococcal disease in the of pneumonia and bacteremia model in mice for the analysis of protective and Pneumococcal Pneumonia A Prospective StudyThe of Bacteria in of infections in patients: Diagnostic and therapeutic from Pneumonia in Children in the United States, of Mortality in Pneumococcal and risk factors for mortality among adults with pneumonia in of the of Blood Cultures or from Patients with Early and of respiratory of pneumococcal capsular conjugate vaccines new and response of pneumococcal need for from invasive pneumococcal pneumonia in the of antibiotic Cultures for Community-Acquired of Streptococcus pneumoniae by capsular and in Patients: of in Patients: of of pneumococcal pneumonia: the case for disease in and current of invasive pneumococcal for pneumococcal infection at the and current and future and the Does Not the or of or in a Model of Pneumococcal Against Streptococcus of Pneumonia in Pneumonia and Bacteremia in a Endocarditis Caused by Streptococcus for New Vaccine with on Pneumococcal Protein A vaccination in adults in of

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