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Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c] pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c] pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists.

Medicinal ChemistryMedicinePharmacological AgentPharmacotherapyDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug DiscoverySelective Activity