Silvio Dionisotti

The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist.

Cristina Zocchi, E. Ongini, Andrea Conti et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 197 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors

E. Ongini, Silvio Dionisotti, Stefania Gessi et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1999 · 185 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +11

Pyrazolo[4,3-<i>e</i>]-1,2,4-triazolo[1,5-<i>c</i>]pyrimidine Derivatives:  Potent and Selective A_2AAdenosine Antagonists

Pier Giovanni Baraldi, Barbara Cacciari, Giampiero Spalluto et al. · Journal of Medicinal Chemistry · 1996 · 112 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Binding of the radioligand [³H]‐SCH 58261, a new non‐xanthine A_2A adenosine receptor antagonist, to rat striatal membranes

Cristina Zocchi, Ennio Ongini, S. D. Ferrara et al. · British Journal of Pharmacology · 1996 · 84 citations · Full text

Medicine, Neuroscience, Pharmacology +15

Synthesis of new pyrazolo[4,3-e]1,2,4-triazolo[1,5-c] pyrimidine and 1,2,3-triazolo[4,5-e]1,2,4-triazolo[1,5-c] pyrimidine displaying potent and selective activity as A2a adenosine receptor antagonists.

Pier Giovanni Baraldi, Stefano Manfredini, Daniele Simoni et al. · Bioorganic & Medicinal Chemistry Letters · 1994 · 83 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13