Concepedia

Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2

Alexis Dunkle, Ivan Dzhagalov, You‐Wen He

Cell Death and Differentiation · 2010 · 40 citations · 42 references

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References

42

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Michael C. Wei, Wei‐Xing Zong, Emily H. Cheng et al. · Science · 2001 · 3.9K citations · Full text

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Movement of Bax from the Cytosol to Mitochondria during Apoptosis

Keith G. Wolter, Yi‐Te Hsu, Carolyn L. Smith et al. · The Journal of Cell Biology · 1997 · 1.8K citations · Full text

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Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

Lin Chen, Simon N. Willis, Andrew H. Wei et al. · Molecular Cell · 2005 · 1.8K citations · Full text

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BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis

Emily H. Cheng, Michael C. Wei, Solly Weiler et al. · Molecular Cell · 2001 · 1.7K citations · Full text

, , +10

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

Anthony Letai, Michael C. Bassik, Loren D. Walensky et al. · Cancer Cell · 2002 · 1.6K citations · Full text

, , +16