The intestinal bioavailability of vaccenic acid and activation of peroxisome proliferator‐activated receptor‐α and ‐γ in a rodent model of dyslipidemia and the metabolic syndrome

Abstract

The activation of PPAR-α- and PPAR-γ-dependent pathways provides a mechanistic explanation of how VA improves blood lipids and related metabolic disorders during conditions of hyperlipidemia. This report also supports the consideration of differential reporting of industrially produced versus natural TFA on food nutrient labels.