Polyhydroxylated pyrrolizidines. Part I: Short and highly stereocontrolled syntheses of hyacinthacines

Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application

Naoki Asano, Robert J. Nash, Russell J. Molyneux et al. · Tetrahedron Asymmetry · 2000 · 1K citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

New polyhydroxylated pyrrolizidine alkaloids from Muscari armeniacum: structural determination and biological activity

Naoki Asano, Hiroyo Kuroi, Kyoko Ikeda et al. · Tetrahedron Asymmetry · 2000 · 150 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Isolation from and x-ray crystal structure of alexine, (1r,2r,3r,7s,8s)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine [(2r,3r,4r,5s,6s)-2-hydroxymethyl-1-azabicyclo[3.3.0]octan-3,4,6-triol], a unique pyrrolizidine alkaloid

Robert J. Nash, Linda E. Fellows, Janet V. Dring et al. · Tetrahedron Letters · 1988 · 126 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Polyhydroxylated pyrrolidine and pyrrolizidine alkaloids from Hyacinthoides non-scripta and Scilla campanulata

Atsushi Kato, Isao Adachi, Miwa Miyauchi et al. · Carbohydrate Research · 1999 · 124 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Synthesis of Novel Glycosidase-Inhibitory Hydroxymethyl-Substituted Polyhydroxylated Indolizidines:  Ring-Expanded Analogs of the Pyrrolizidine Alkaloids Alexine and Australine

William H. Pearson, Erik J. Hembre · The Journal of Organic Chemistry · 1996 · 72 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13