Yeast centromere DNA is in a unique and highly ordered structure in chromosomes and small circular minichromosomes

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

Peter Rigby, Marianne Dieckmann, Carl Rhodes et al. · Journal of Molecular Biology · 1977 · 11.7K citations

Life Sciences, Molecular Biology, Molecular Genetics +14

Transformation of yeast.

A. Hinnen, James Hicks, Gerald R. Fink · Proceedings of the National Academy of Sciences · 1978 · 2.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis

Tom Maniatis, Andrea Jeffrey, Hans Van deSande · Biochemistry · 1975 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +9

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

Carl Wu · Nature · 1980 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +9