Concepedia

A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth

Gerene M. Denning, B Jean-Joseph, Chengyu Prince, Donald L. Durden, Peter K. Vogt

Oncogene · 2007 · 104 citations · 24 references

DOI

Concepts

References

24

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

, , +16

The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate

Tomohiko Maehama, Jack E. Dixon · Journal of Biological Chemistry · 1998 · 3.1K citations · Full text

, , +17

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Peter A. Steck, Mark A. Pershouse, Samar A. Jasser et al. · Nature Genetics · 1997 · 2.8K citations

, , +11

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

Michael P. Myers, Ian Pass, Ian H. Batty et al. · Proceedings of the National Academy of Sciences · 1998 · 1.2K citations

, , +15

TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta.

Dongmei Li, Hong Sun · PubMed · 1997 · 875 citations

, , +13