Syk Mediates IL−17-Induced CCL20 Expression by Targeting Act1-Dependent K63-Linked Ubiquitination of TRAF6

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

Ivan Zanoni, Renato Ostuni, Lorri R. Marek et al. · Cell · 2011 · 991 citations · Full text

Life Sciences, Cell Biology, Immunology +14

Essential function for the kinase TAK1 in innate and adaptive immune responses

Shintaro Sato, Hideki Sanjo, Kiyoshi Takeda et al. · Nature Immunology · 2005 · 968 citations

Life Sciences, Immunology, Molecular Biology +16

Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways

Kristine Nograles, Lisa C. Zaba, Emma Guttman‐Yassky et al. · British Journal of Dermatology · 2008 · 799 citations · Full text

Medicine, Dermatology, Immunology +17

Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis

Andrea Chiricozzi, Emma Guttman‐Yassky, Mayte Suárez‐Fariñas et al. · Journal of Investigative Dermatology · 2010 · 670 citations · Full text

Life Sciences, Dermatology, Immunology +16

TAB2, a Novel Adaptor Protein, Mediates Activation of TAK1 MAPKKK by Linking TAK1 to TRAF6 in the IL-1 Signal Transduction Pathway

Giichi Takaesu, Satoshi Kishida, Atsushi Hiyama et al. · Molecular Cell · 2000 · 608 citations · Full text

Life Sciences, Immunology, Molecular Biology +16