Scaling laws in the functional content of genomes

Gene Ontology: tool for the unification of biology

Michael Ashburner, Catherine A. Ball, Judith A. Blake et al. · Nature Genetics · 2000 · 44.6K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +9

Network Motifs: Simple Building Blocks of Complex Networks

Ron Milo, Shai S. Shen-Orr, Shalev Itzkovitz et al. · Science · 2002 · 7.5K citations

Life Sciences, Neurobiology, Neuroscience +14

A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

Peter Uetz, Loïc Giot, Gerard Cagney et al. · Nature · 2000 · 4.7K citations

Life Sciences, Biochemistry, Molecular Biology +16

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen

C. Kendall Stover, X. Q. Pham, Alice L. Erwin et al. · Nature · 2000 · 4.6K citations · Full text

Life Sciences, Genetics, Microbiology +13

A comprehensive two-hybrid analysis to explore the yeast protein interactome

Takashi Ito, Tomoko Chiba, Ritsuko Ozawa et al. · Proceedings of the National Academy of Sciences · 2001 · 3.6K citations · Full text

Life Sciences, Bioinformatics, Biology +13