Concepedia

Comparison of the effects of the synthetic pyrethroid Metofluthrin and phenobarbital on CYP2B form induction and replicative DNA synthesis in cultured rat and human hepatocytes

Y Hirose, Hirohisa Nagahori, Tomoya Yamada, Yoshihito Deguchi, Yoshitaka Tomigahara, Kazuhiko Nishioka, Satoshi Uwagawa, Satoshi Kawamura, Naohiko Isobe, Brian G. Lake,

Toxicology · 2009 · 56 citations · 22 references

DOI

Concepts

References

22

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans

A. J. Zuckerman · Journal of Clinical Pathology · 1995 · 8.8K citations · Full text

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The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene

Tatsuya Sueyoshi, Takeshi Kawamoto, Igor N. Zelko et al. · Journal of Biological Chemistry · 1999 · 671 citations · Full text

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The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

Ping Wei, Jun Zhang, Margarete Egan-Hafley et al. · Nature · 2000 · 649 citations

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The Orphan Nuclear Receptor Constitutive Active/Androstane Receptor Is Essential for Liver Tumor Promotion by Phenobarbital in Mice

Yukio Yamamoto, Rick Moore, Thomas L. Goldsworthy et al. · Cancer Research · 2004 · 346 citations

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Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes

Ajay Madan, Richard Graham, Kathleen Carroll et al. · Drug Metabolism and Disposition · 2003 · 337 citations

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