Hirohisa Nagahori

Human Hepatocytes Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogen Sodium Phenobarbital in an In Vivo Study Using a Chimeric Mouse with Humanized Liver

Tomoya Yamada, Yu Okuda, Masahiko Kushida et al. · Toxicological Sciences · 2014 · 78 citations · Full text

Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation

Yoshihito Deguchi, Tomoya Yamada, Y Hirose et al. · Toxicological Sciences · 2009 · 71 citations · Full text

Pathology, Cell Death, Hepatic Cyp2b Induction +21

Comparison of the effects of the synthetic pyrethroid Metofluthrin and phenobarbital on CYP2B form induction and replicative DNA synthesis in cultured rat and human hepatocytes

Y Hirose, Hirohisa Nagahori, Tomoya Yamada et al. · Toxicology · 2009 · 55 citations

Molecular Pharmacology, Cyp2b Form Induction, Replicative Dna Synthesis +7

An in Vitro Reporter Gene Assay Method Incorporating Metabolic Activation with Human and Rat S9 or Liver Microsomes

Kayo Sumida, Norihisa Ooe, Hirohisa Nagahori et al. · Biochemical and Biophysical Research Communications · 2001 · 43 citations

Systems Biology, Rat S9, Reporter Gene Assay +11

Quantitative Structure–Activity Relationship Model for the Fetal–Maternal Blood Concentration Ratio of Chemicals in Humans

Tomoyuki Takaku, Hirohisa Nagahori, Yoshihisa Sogame et al. · Biological and Pharmaceutical Bulletin · 2015 · 33 citations · Full text

Fetal Medicine, Placental Transfer, Bioanalysis +23