An in Vitro Reporter Gene Assay Method Incorporating Metabolic Activation with Human and Rat S9 or Liver Microsomes

The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants.

Ana M. Soto, Carlos Sonnenschein, KunMo Chung et al. · Environmental Health Perspectives · 1995 · 1.7K citations · Full text

Pharmacy, Environmental Sciences, Toxicology +17

Evaluation of Chemicals with Endocrine Modulating Activity in a Yeast-Based Steroid Hormone Receptor Gene Transcription Assay

Kevin W. Gaido, Linda S. Leonard, Stephanie Lovell et al. · Toxicology and Applied Pharmacology · 1997 · 655 citations

Life Sciences, Biochemistry, Molecular Biology +12

Assessing environmental chemicals for estrogenicity using a combination of in vitro and in vivo assays.

Michael D. Shelby, Retha R. Newbold, Douglas Β. Tully et al. · Environmental Health Perspectives · 1996 · 433 citations · Full text

Pharmacy, Endocrinology, Toxicology +17

New Screening Methods for Chemicals with Hormonal Activities Using Interaction of Nuclear Hormone Receptor with Coactivator

Jun‐ichi Nishikawa, Koichi Saito, Jun Goto et al. · Toxicology and Applied Pharmacology · 1999 · 333 citations

Life Sciences, Biochemistry, Pharmacology +16

Studies on the in vivo and in vitro estrogenic activities of methoxychlor and its metabolites. Role of hepatic mono-oxygenase in methoxychlor activation

William H. Bulger, Roseanna M. Muccitelli, David Kupfer · Biochemical Pharmacology · 1978 · 242 citations

Life Sciences, Pharmacology, Toxicology +13