Concepedia
Neuroscience · 1993 · 86 citations · 54 references
Life SciencesNeurobiologyNeuroscienceCellular NeurobiologyCellular NeuroscienceNeurochemistryAmyloid FormationGabaergic NeurochemistryGabaergic SignalingNervous TissueNeuronal Cell DeathNeuroprotectionAmyloid ToxicityAmyloid-beta-induced NeurotoxicityGabaergic Synaptic Toxicity
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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
Alison Goate, Marie‐Christine Chartier‐Harlin, Jeremy Brown et al. · Nature · 1991 · 4.6K citations
Life Sciences, Genetics, Molecular Genetics +16
Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides
Bruce A. Yankner, Lawrence K. Duffy, Daniel A. Kirschner · Science · 1990 · 2K citations
Life Sciences, Neurobiology, Neuroscience +17
Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production
Martin Citron, Tilman Oltersdorf, Christian Haass et al. · Nature · 1992 · 1.7K citations
Life Sciences, Molecular Biology, Neurology +16
beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
MP Mattson, Bin Cheng, David L. Davis et al. · Journal of Neuroscience · 1992 · 1.6K citations · Full text
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state
Daniel Burdick, AJ Walencewicz, CG Glabe et al. · Journal of Neuroscience · 1993 · 1.4K citations · Full text