Trends in Evolutionary Biology · 2012 · 53 citations · 0 references
Life SciencesBioinformaticsEvolutionary BiologyMolecular EvolutionPhylogeneticsSequence AnalysisCodon EvolutionCodon RecognitionPhylogenetic AnalysisProtein EvolutionProtein Sequence AnalysisSequence EvolutionCodon AdaptationCodon Evolution In Protein-coding GenesCodon Substitution ModelsCodon Usage DynamicsCodon Usage EvolutionComparative Codon EvolutionContext-dependent Codon EvolutionProtein Sequence Evolution
The unifying principle in almost all of bioinformatics is sequence analysis: no matter if you are predicting the structure of proteins, analyzing the genetic variation in a population, or deciphering the evolutionary history of your favorite gene, your analysis hinges on looking at biological sequences and how they change over time, between species, or from gene to gene. Biological sequence analysis is the cornerstone.