Codon Usage Evolution is a molecular evolutionary phenomenon characterized by changes in the preferential use of synonymous codons within microbial genomes over time, driven by the interplay of mutation, selection, and genetic drift.
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Jeffrey L. Bennetzen, B. D. Hall · Journal of Biological Chemistry · 1982 · 1.6K citations · Full text
Codon usage in bacteria: correlation with gene expressivity
Manolo Gouy, Christian Gautier · Nucleic Acids Research · 1982 · 1.3K citations · Full text
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