Concepedia

Codon Substitution Models

Codon Substitution Models is a mathematical framework in molecular evolution that describes the process of nucleotide substitutions at the codon level by specifying instantaneous rates of change between codons, distinguishing it from nucleotide- or amino acid-level models through its explicit incorporation of the genetic code and selection pressures acting on protein-coding sequences.

202

Publications

32.9K

Citations

507

Authors

259

Institutions

Publications per year

2017–2026

36

Parents

Publications

202

Amino Acid Difference Formula to Help Explain Protein Evolution

Richard Grantham · Science · 1974 · 2.4K citations

, , +17

Codon-Substitution Models for Heterogeneous Selection Pressure at Amino Acid Sites

Ziheng Yang, Rasmus Nielsen, Nick Goldman et al. · Genetics · 2000 · 2.4K citations · Full text

, , +14

CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model

Liguo Wang, Hyun Jung Park, Surendra Dasari et al. · Nucleic Acids Research · 2013 · 2.2K citations · Full text

, , +14

Evaluation of an Improved Branch-Site Likelihood Method for Detecting Positive Selection at the Molecular Level

J. Zhang · Molecular Biology and Evolution · 2005 · 1.9K citations · Full text

, , +13

Likelihood Models for Detecting Positively Selected Amino Acid Sites and Applications to the HIV-1 Envelope Gene

Rasmus Nielsen, Ziheng Yang · Genetics · 1998 · 1.7K citations · Full text

, , +12

1–5 of 202

Authors

507

  1. ZY
    Ziheng Yang

    University College London, United Kingdom

    13 publications · 8.6K citations

    13

    h-index

  2. NG
    Nick Goldman

    European Bioinformatics Institute, United Kingdom

    9 publications · 3K citations

    9

    h-index

  3. RN
    Rasmus Nielsen

    University of California, Berkeley, United States

    9 publications · 7.1K citations

    9

    h-index

  4. MA
    Maria Anisimova

    SIB Swiss Institute of Bioinformatics, Switzerland

    8 publications · 2.3K citations

    8

    h-index

  5. SL
    Sergei L. Kosakovsky Pond

    University of California San Diego, United States

    8 publications · 1.3K citations

    8

    h-index

1–5 of 507

Institutions

259

  1. University College London

    London, United Kingdom

    16 h-index

    25 publications

    11.7K citations

  2. Université Claude Bernard Lyon 1

    Villeurbanne, France

    10 h-index

    20 publications

    3.2K citations

  3. SIB Swiss Institute of Bioinformatics

    Lausanne, Switzerland

    10 h-index

    19 publications

    1.4K citations

  4. European Bioinformatics Institute

    Cambridge, United Kingdom

    10 h-index

    14 publications

    1.1K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    19 publications

    886 citations

  6. Dalhousie University

    Halifax, Canada

    7 h-index

    25 publications

    1.8K citations

  7. Laboratoire de Biométrie et Biologie Evolutive

    Villeurbanne, France

    7 h-index

    15 publications

    691 citations

  8. University of California San Diego

    San Diego, United States

    7 h-index

    22 publications

    6.3K citations

1–8 of 259

Venues

  1. Molecular Biology and Evolution

    MBE · 52 publications · 11.1K citations

    36

    h-index

  2. Genetics

    11 publications · 5.7K citations

    11

    h-index

  3. BMC Evolutionary Biology

    10 publications · 459 citations

    10

    h-index

  4. Systematic Biology

    10 publications · 1.1K citations

    10

    h-index

  5. Journal of Molecular Evolution

    10 publications · 528 citations

    10

    h-index

1–5