Concepedia

TCR Binding to Peptide-MHC Stabilizes a Flexible Recognition Interface

Benjamin E. Willcox, George F. Gao, Jessica R. Wyer, John E. Ladbury, John I. Bell, Bent K. Jakobsen, P. Anton van der Merwe

Immunity · 1999 · 307 citations · 34 references

Open access

Concepts

Life SciencesImmunologyMolecular BiologyMolecular ImmunologyMolecular RecognitionSignal TransductionAntigen PresentationAntigen RecognitionMajor Histocompatibility ComplexProtein-ligand RecognitionReceptor-ligand InteractionsT Cell ActivationMajor Histocompatibility Complex (Mhc) PresentationMhc Antigen PresentationMhc-peptide RecognitionPeptide Antigen RecognitionPeptide-major Histocompatibility Complex RecognitionPeptide-mhc StabilityT Cell Receptor Recognition

References

34

Handbook of Experimental Immunology.

Annals of Internal Medicine · 1968 · 2.4K citations · Full text

Life Sciences, Immunology, Pathobiology +12

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

Alain Townsend · Cell · 1986 · 1.7K citations

Life Sciences, Immunology, Molecular Biology +15

Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

Kai W. Wucherpfennig, Jack L. Strominger · Cell · 1995 · 1.5K citations · Full text

Life Sciences, Immunology, Pathology +17

HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides.

David N. Garboczi, Deborah T. Hung, Don C. Wiley · Proceedings of the National Academy of Sciences · 1992 · 701 citations

Life Sciences, Biochemistry, Immunology +15

Handbook of experimental immunology

Frank Emmrich · Immunology Today · 1986 · 693 citations

Medicine, Hematology, Immunology +11