Concepedia

Aggregates of oxidized proteins (lipofuscin) induce apoptosis through proteasome inhibition and dysregulation of proapoptotic proteins

Saul R. Powell, Ping Wang, András Divald, Saul Teichberg, Viraga Haridas, Thomas W. McCloskey, Kelvin J.A. Davies, Harvey L. Katzeff

Free Radical Biology and Medicine · 2005 · 113 citations · 38 references

DOI

Concepts

References

38

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

, , +14

Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

Yutaka Eguchi, S Shimizu, Yoshihide Tsujimoto · PubMed · 1997 · 1.3K citations

, , +16

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

Kui Lei, Roger J. Davis · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

, , +16

Degradation of oxidized proteins in mammalian cells

Tilman Grune, Thomas Reinheckel, Kelvin J.A. Davies · The FASEB Journal · 1997 · 831 citations

, , +17