Concepedia

Publication | Open Access

Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin

DOIFull Paper Access

105

Citations

45

References

2013

Year

Shun‐ichiro Asahara, Yuki Shibutani, Kyoko Teruyama, Hiroyuki Inoue, Yukina Kawada, Hiroaki Etoh, Tomokazu Matsuda, Maki Kimura-Koyanagi, N. Hashimoto, Mizuho Sakahara,
Diabetologia

Abstract

In RAC1-deficient pancreatic beta cells, F-actin acts as a barrier for insulin granules and reduces glucose-stimulated insulin secretion.

References

YearCitations

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