Neuroprotection and mechanisms of atractylenolide III in preventing learning and memory impairment induced by chronic high-dose homocysteine administration in rats

Place navigation impaired in rats with hippocampal lesions

Richard Morris, Paul Garrud, J. N. P. Rawlins et al. · Nature · 1982 · 6.4K citations

Life Sciences, Neurobiology, Neuroscience +14

Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease

Sudha Seshadri, Alexa Beiser, Jacob Selhub et al. · New England Journal of Medicine · 2002 · 3.2K citations · Full text

Medicine, Geriatric Medicine, Nutritional Sciences +15

Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis

Reiner U. Jänicke, Michael L. Sprengart, Mas Rina Wati et al. · Journal of Biological Chemistry · 1998 · 2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Folate, Vitamin B12, and Serum Total Homocysteine Levels in Confirmed Alzheimer Disease

Robert Clarke, A. David Smith, Kim A. Jobst et al. · Archives of Neurology · 1998 · 1.4K citations

Medicine, Geriatric Medicine, Aging +16

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

Timothy H. Murphy, Masaomi Miyamoto, Antonio Sastre et al. · Neuron · 1989 · 1K citations

Life Sciences, Neuroscience, Pharmacology +17