Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

Patricia Z. O’Farrell, Howard M. Goodman, Patrick H. O’Farrell · Cell · 1977 · 3.5K citations

Life Sciences, Biochemistry, Molecular Biology +12

[42] Detection and quantification of phosphotyrosine in proteins

Jonathan A. Cooper, Bartholomew M. Sefton, Tony Hunter · Methods in enzymology on CD-ROM/Methods in enzymology · 1983 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +10

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

John B. Imboden, John D. Stobo · The Journal of Experimental Medicine · 1985 · 732 citations

Life Sciences, Biochemistry, Immunology +17

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.

Claude Cochet, Gordon N. Gill, Jill Meisenhelder et al. · Journal of Biological Chemistry · 1984 · 715 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15