John B. Imboden

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

John B. Imboden, John D. Stobo · The Journal of Experimental Medicine · 1985 · 732 citations

T-regulatory Cell, Immunology, Ca2+ Ionophore +16

Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium.

Anna Weiss, John B. Imboden, Dolores Shoback et al. · Proceedings of the National Academy of Sciences · 1984 · 447 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +21

The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium.

John B. Imboden, Arthur Weiss, John D. Stobo · The Journal of Immunology · 1985 · 221 citations

Immunology, Immunodominance, Immunologic Mechanism +16

CD28 Mediates Transcriptional Upregulation of the Interleukin-2 (IL-2) Promoter through a Composite Element Containing the CD28RE and NF-IL-2B AP-1 Sites

Virginia Smith Shapiro, Kenneth E. Truitt, John B. Imboden et al. · Molecular and Cellular Biology · 1997 · 214 citations · Full text

Composite Element, T-regulatory Cell, Immunology +18

Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and <i>gamma</i>-interferon genes.

R Wiskocil, Amélie Weiss, John B. Imboden et al. · The Journal of Immunology · 1985 · 202 citations · Full text