Concepedia

A negative feedback signaling network underlies oncogene-induced senescence

Stéphanie Courtois-Cox, Sybil M. Genther Williams, Elizabeth E. Reczek, Bryan W. Johnson, Lauren T. McGillicuddy, Cory M. Johannessen, Pablo E. Hollstein, Mia MacCollin, Karen Cichowski

Cancer Cell · 2006 · 484 citations · 36 references

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36

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

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Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

, , +10

BRAFE600-associated senescence-like cell cycle arrest of human naevi

Chrysiis Michaloglou, Liesbeth C.W. Vredeveld, Marı́a S. Soengas et al. · Nature · 2005 · 2.1K citations · Full text

, , +12

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Zhenbang Chen, Lloyd C. Trotman, David R. Shaffer et al. · Nature · 2005 · 2K citations · Full text

, , +16

Senescence in premalignant tumours

Manuel Collado, Jesús Gil, Alejo Efeyan et al. · Nature · 2005 · 1.5K citations

, , +12