Concepedia

Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase

Terrence M. Ciccarone, Suzanne C. MacTough, Theresa M. Williams, Christopher J. Dinsmore, Timothy J. O’Neill, Daksha Shah, Joseph Culberson, Kenneth S. Koblan, Nancy E. Kohl, Allen Oliff,

Bioorganic & Medicinal Chemistry Letters · 1999 · 33 citations · 23 references

DOIFull text

Open access

Concepts

References

23

Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics

F. MOHAMADI, Nigel G. J. Richards, Wayne C. Guida et al. · Journal of Computational Chemistry · 1990 · 3.8K citations

, , +13

Inhibition of purified p21 farnesyl:protein transferase by Cys-AAX tetrapeptides

Yuval Reiss, Joseph L. Goldstein, Miguel C. Seabra et al. · Cell · 1990 · 815 citations

, , +9

Selective Inhibition of <i>ras</i> -Dependent Transformation by a Farnesyltransferase Inhibitor

Nancy E. Kohl, Scott D. Mosser, S. J. DESOLMS et al. · Science · 1993 · 582 citations

, , +13

Sequence dependence of protein isoprenylation

Sheri L. Moores, Michael D. Schaber, S.D. Mosser et al. · Journal of Biological Chemistry · 1991 · 582 citations · Full text

, , +8

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

Nancy E. Kohl, Charles A. Omer, Michael W. Conner et al. · Nature Medicine · 1995 · 539 citations

, , +11