P2Y12, a New Platelet ADP Receptor, Target of Clopidogrel

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

George Scatchard · Annals of the New York Academy of Sciences · 1949 · 19.9K citations

Natural Sciences, Biophysics, Chemistry +9

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

Peter J. Munson, David Rodbard · Analytical Biochemistry · 1980 · 8.5K citations

Life Sciences, Chemistry, Biomolecular Modeling +11

A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)

The Lancet · 1996 · 6.5K citations

Medicine, Pharmacology, Pharmacotherapy +10

Identification of the platelet ADP receptor targeted by antithrombotic drugs

Gunther Hollopeter, Hans‐Michael Jantzen, D Vincent et al. · Nature · 2001 · 1.4K citations

Medicine, Hematology, Pharmacology +14