Concepedia

Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity

Praveen Rajendran, Manu Jaggi, Manoj Kumar Singh, Rama Mukherjee, Anand C. Burman

Investigational New Drugs · 2007 · 69 citations · 33 references

DOI

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References

33

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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Timing of New Black Box Warnings and Withdrawals for Prescription Medications

Karen E. Lasser · JAMA · 2002 · 1K citations

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Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

Emily Pisha, Heebyung Chai, Ik‐Soo Lee et al. · Nature Medicine · 1995 · 886 citations

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Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells

Valentina Zuco, Rosanna Supino, Sabina Carla Righetti et al. · Cancer Letters · 2002 · 530 citations

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Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors.

Simone Fulda, Claudia Friesen, Carsten Scaffidi et al. · PubMed · 1997 · 348 citations · Full text

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