Journal of Water Resource and Protection · 2014 · 13 citations · 15 references
Natural SciencesEnvironmental SciencesToxicologyAnalytical ToxicologyEcotoxicologyEnvironmental ToxicologyAquatic EcotoxicologyEnvironmental HepatotoxicantsEnvironmental HepatotoxinsHepatotoxicity MechanismsWater PollutionWater QualityConcentrationDrinking Water Contaminant HepatotoxicityLiver Tumor PromotionMicrocystin HepatotoxicityMicrocystin ToxicologySpeciation In Water Samples
Microcystins cause acute hepatotoxicity and chronic liver tumor promotion. This study presents the results of HPLC DAD analyses and their LC-MS confirmation of samples from five Bulgarian water bodies (reservoirs Stoudena, Pchelina, Bistritsa and lakes Dourankoulak, Vaya). The total concentration of microcystins in water samples ranged from 0.1 to 26.5 g/l. The amount of microcystins in the biomasses ranged from 11.4 to 49.6 g/g (d.w.). The high percent of positive samples in which the most toxic microcystin-LR is recorded, can serve as a strong alarm for the necessity of a serious study and relevant discussion of the problem with responsible authorities at national level.
15
Lisa Spoof, Pia Vesterkvist, Tore Lindholm et al. · Journal of Chromatography A · 2003 · 218 citations