A mutated cathepsin-D devoid of its catalytic activity stimulates the growth of cancer cells

Active human immunodeficiency virus protease is required for viral infectivity.

Nancy E. Kohl, Emilio A. Emini, William A. Schleif et al. · Proceedings of the National Academy of Sciences · 1988 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines

Erik W. Thompson, Soonmyoung Paik, Nils Brünner et al. · Journal of Cellular Physiology · 1992 · 525 citations

Medicine, Cell Biology, Oncology +13

Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin A.

S Seelmeier, Heike Schmidt, Vito Türk et al. · Proceedings of the National Academy of Sciences · 1988 · 326 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Cloning and sequence analysis of cDNA for human cathepsin D.

Phyllis L. Faust, Stuart Kornfeld, John M. Chirgwin · Proceedings of the National Academy of Sciences · 1985 · 320 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Hormonal effects on intracellular and secreted casein in cultures of mouse mammary epithelial cells on floating collagen membranes.

Joanne T. Emerman, Jumpei Enami, Dorothy R. Pitelka et al. · Proceedings of the National Academy of Sciences · 1977 · 290 citations · Full text

Life Sciences, Cell Biology, Endocrinology +16