Concepedia

Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis

Weijie Zhou, Zhen Geng, Shan Chi, Wenli Zhang, Xiao-Feng Niu, Shu-Jue Lan, Li Ma, Xuesong Yang, Lijing Wang, Yanqing Ding,

Cell Research · 2011 · 137 citations · 67 references

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67

Slit Proteins Bind Robo Receptors and Have an Evolutionarily Conserved Role in Repulsive Axon Guidance

Katja Brose, K Bland, Kuan Hong Wang et al. · Cell · 1999 · 1.2K citations · Full text

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Roundabout Controls Axon Crossing of the CNS Midline and Defines a Novel Subfamily of Evolutionarily Conserved Guidance Receptors

Thomas Kidd, Katja Brose, Kevin J. Mitchell et al. · Cell · 1998 · 894 citations · Full text

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Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

Yasuyuki Fujita, Gerd Krause, Martin Scheffner et al. · Nature Cell Biology · 2002 · 831 citations

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Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion

Zhimin Lu, Sourav Ghosh, Zhiyong Wang et al. · Cancer Cell · 2003 · 649 citations · Full text

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Signal Transduction in Neuronal Migration

Kit Wong, Xiu-Rong Ren, Yang-Zhong Huang et al. · Cell · 2001 · 555 citations · Full text

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