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Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity

Sebastian Häusler, I Montalban del Barrio, Jenny Strohschein, P. Anoop Chandran, J. Engel, A Hönig, Monika Ossadnik, Evi Horn, Birgitt Fischer, Mathias Krockenberger,

Cancer Immunology Immunotherapy · 2011 · 190 citations · 37 references

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37

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Tyler J. Curiel, George Coukos, Linhua Zou et al. · Nature Medicine · 2004 · 5.1K citations

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Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer

Lin Zhang, José R. Conejo-García, Dionyssios Katsaros et al. · New England Journal of Medicine · 2003 · 3.4K citations · Full text

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

Silvia Deaglio, Karen M. Dwyer, Wenda Gao et al. · The Journal of Experimental Medicine · 2007 · 2.4K citations · Full text

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Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

Michael R. Elliott, Faraaz B. Chekeni, Paul C. Trampont et al. · Nature · 2009 · 1.6K citations · Full text

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Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression

Giovanna Borsellino, Markus Kleinewietfeld, Diletta Di Mitri et al. · Blood · 2007 · 1.3K citations · Full text

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